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totally wired cell@cell@outerheaven.club (2026-10-01 17:05:32)
> Treatment-resistant depression (TRD) is often defined as major depressive disorder in which an affected person does not respond adequately to at least two different antidepressant medications at an adequate dose and for an adequate duration.
> Inadequate response has most commonly been defined as less than 25% reduction in depressive symptoms following treatment with an antidepressant.

ach so, so the threshold is 25%..anything above that is considered a “success” :sadcat: